CD45.2 anticorps

N° du produit ABIN135324

Cet anticorps anti-CD45.2 est un anticorps Souris Monoclonal détectant CD45.2 dans FACS, IHC et IHC (fro). Adapté pour Souris.

Aperçu rapide pour CD45.2 anticorps (ABIN135324)

Antigène: CD45.2 (CD45 (CD45.2 Allogen))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD45.2 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 104

Détail du produit anti-CD45.2 anticorps

Specificité: Mouse CD45.2, Mr 180-240 kDa

Attributs du produit: Mouse Anti-Mouse CD45.2-UNLB

Purification: Purified

Immunogène: B10.S mouse thymocytes and splenocytes

Isotype: IgG2a

Information d'application

Indications d'application:

• Applications: FC - Quality tested , IHC-FS - Reported in literature
• Working Dilutions: Flow Cytometry FITC, BIOT, and AF488 conjugates 1 g/106 cells PE, APC, SPRD, CY5, PE/CY5.5, PE/CY7, APC/CY5.5, AF647, 0.3 g/106 cells AF700, and PACBLU conjugates For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Volume d'échantillon: 1 mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Agent conservateur: Without preservative

Conseil sur la manipulation: Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C

Détails sur CD45.2

Antigène: CD45.2 (CD45 (CD45.2 Allogen))

Autre désignation: CD45.2

Sujet: The CD45 antigen is an essential regulator of leukocyte activation and development, and is now known to be a protein tyrosine phosphatase, e.g. CD45 is able to dephosporylate the Src family of protein kinases. This activity is now known to be required for signal transduction induced by T and B cell antigen receptor engagement, cytokine signaling and Fc receptor stimulation. The functional state of CD45 also has a pronounced effect on lymphocyte development. CD45 exists in multiple forms, such as the restricted variants (CD45R) and as allelic forms CD45.1/Ly-5.1 and CD45.2/Ly-5.2. The specificity of antibodies to CD45.1 and CD45.2 has been exploited in studies where resolution of donor and recipient cells is essential, such as in gene therapy or bone marrow transplantation.