CD43 anticorps (SPRD)
Aperçu rapide pour CD43 anticorps (SPRD) (ABIN135776)
Antigène
Voir toutes CD43 (SPN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Marque
- Spectral Red ™
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Specificité
- Human CD43, Mr 95-135 kDa
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Attributs du produit
- Mouse Anti-Human CD43-SPRD
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Immunogène
- KG-1 cells
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Isotype
- IgG1
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Indications d'application
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- Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , WB - Reported in literature , Adhesion - Reported in literature
- Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, PE, APC, and SPRD conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
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Restrictions
- For Research Use only
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Buffer
- 100 tests in 1.0 mL of PBS/Sodium azide and a stabilizing agent
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
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Do not freeze!
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed. -
Stock
- 4 °C
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Stockage commentaire
- Store at 2-8°C
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- CD43 (SPN) (Sialophorin (SPN))
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Autre désignation
- CD43
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Sujet
- CD43, a member of the sialomucin family of cell surface receptors, is a 95-135 kDa type I transmembrane glycoprotein whose variability in molecular weight is dependent upon the nature of the extracellular O-glycans. It is the major sialoglycoprotein on thymocytes, T cells and neutrophils. It is also present on activated B cells, plasma cells, NK cells, granulocytes, monocytes, macrophages, platelets and bone marrow hematopoietic stem cells. CD43, which binds to ICAM-1 (CD54), appears to function as an anti-adhesion molecule, inhibiting T cell interactions, including T cell killing, and by increasing the threshold for T cell activation.
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Pathways
- Regulation of Leukocyte Mediated Immunity
Antigène
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