CD51 anticorps

N° du produit ABIN135791

L’anticorps Souris Monoclonal anti-CD51 a été validé pour IHC et FACS. Il convient pour détecter CD51 dans des échantillons de Humain.

Aperçu rapide pour CD51 anticorps (ABIN135791)

Antigène: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD51 est non-conjugé

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 13C2

Détail du produit anti-CD51 anticorps

Specificité: Human/African Green Monkey/Rabbit/Bovine CD51, Mr 125 & 24 kDa

Attributs du produit: Mouse Anti-Human CD51-UNLB

Purification: Purified

Immunogène: Cell suspension containing osteoclasts from osteoclastomas

Isotype: IgG1

Information d'application

Indications d'application: Working Dilution:
FACS: 1 µg/10^6 cells
Representative data are included in this product insert.

Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Volume d'échantillon: 1 mL

Restrictions: For Research Use only

Stockage

Buffer: Product is supplied as 0.1 mg purified immunoglobulin in 1.0 mL of phosphate buffered saline containing 0.1 % PBS / NaN3 and a stabilizing agent.

Conseil sur la manipulation: Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Détails sur CD51

Antigène: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Autre désignation: CD51

Sujet: CD51 represents the 150 kDa integrin V chain that associates with integrin 3 (CD61) to form the CD51/CD61 vitronectin receptor on endothelial cells, certain activated leukocytes, NK cells, macrophages, neutrophils and platelets. CD51 is the most promiscuous integrin a subunit, it can form heterodimers with the 1 (CD29), 3 (CD61), 5, 6 and 8 subunits in various tissues. CD51/CD61 acts as an activation-independent receptor for platelet attachment and spreading on vitronectin and other RGD-containing proteins, including matrix components. It also mediates leukocyte-endothelial cell adhesion via interaction with CD31.

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex