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CD2 anticorps

Cet anticorps anti-CD2 est un anticorps Souris Monoclonal détectant CD2 dans FACS, IHC et Func. Adapté pour Humain. Ce Primary Antibody a été cité dans 7+ publications.
N° du produit ABIN1383690

Aperçu rapide pour CD2 anticorps (ABIN1383690)

Antigène

Voir toutes CD2 Anticorps
CD2

Reactivité

  • 175
  • 51
  • 30
  • 16
  • 13
  • 11
  • 8
  • 7
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 145
  • 57
  • 34
  • 3
  • 2
  • 1
  • 1
Souris

Clonalité

  • 182
  • 55
  • 5
Monoclonal

Conjugué

  • 111
  • 27
  • 21
  • 19
  • 11
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp CD2 est non-conjugé

Application

  • 179
  • 64
  • 59
  • 47
  • 44
  • 34
  • 32
  • 15
  • 14
  • 12
  • 10
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunohistochemistry (IHC), Functional Studies (Func)

Clone

B-E2
  • Specificité

    Recognises the Lymphocyte Function associated Antigen-2 (LFA-2), a 50 kDa protein

    Purification

    Ion exchange chromatography

    Stérilité

    0.22 μm filtered

    Immunogène

    Human thymocytes,Myeloma X63/AG.8653 x Balb/c spleen cells

    Isotype

    IgG2b, kappa

    Biological Activity Comment

    Inhibits mixed lymphocyte culture
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

    Agent conservateur

    Without preservative

    Stock

    4 °C

    Stockage commentaire

    Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
  • Dupuis-Girod, Cancrini, Le Deist, Palma, Bodemer, Puel, Livadiotti, Picard, Bossuyt, Rossi, Fischer, Casanova: "Successful allogeneic hemopoietic stem cell transplantation in a child who had anhidrotic ectodermal dysplasia with immunodeficiency." dans: Pediatrics, Vol. 118, Issue 1, pp. e205-11, (2006) (PubMed).

    Tiberghien, Ferrand, Lioure, Milpied, Angonin, Deconinck, Certoux, Robinet, Saas, Petracca, Juttner, Reynolds, Longo, Hervé, Cahn: "Administration of herpes simplex-thymidine kinase-expressing donor T cells with a T-cell-depleted allogeneic marrow graft." dans: Blood, Vol. 97, Issue 1, pp. 63-72, (2001) (PubMed).

    Przepiorka, Phillips, Ratanatharathorn, Cottler-Fox, Sehn, Antin, LeBherz, Awwad, Hope, McClain: "A phase II study of BTI-322, a monoclonal anti-CD2 antibody, for treatment of steroid-resistant acute graft-versus-host disease." dans: Blood, Vol. 92, Issue 11, pp. 4066-71, (1999) (PubMed).

    Jabado, de Graeff-Meeder, Cavazzana-Calvo, Haddad, Le Deist, Benkerrou, Dufourcq, Caillat, Blanche, Fischer: "Treatment of familial hemophagocytic lymphohistiocytosis with bone marrow transplantation from HLA genetically nonidentical donors." dans: Blood, Vol. 90, Issue 12, pp. 4743-8, (1997) (PubMed).

    Cavazzana-Calvo, Bordigoni, Michel, Esperou, Souillet, Leblanc, Stephan, Vannier, Mechinaud, Reiffers, Vilmer, Landman-Parker, Benkerrou, Baruchel, Pico, Bernaudin, Bergeron, Plouvier, Thomas, Wijdenes, Lacour, Blanche, Fischer: "A phase II trial of partially incompatible bone marrow transplantation for high-risk acute lymphoblastic leukaemia in children: prevention of graft rejection with anti-LFA-1 and anti-CD2 antibodies. Société Française de Greffe de Moelle Osseuse." dans: British journal of haematology, Vol. 93, Issue 1, pp. 131-8, (1996) (PubMed).

    Jabado, Le Deist, Cant, De Graeff-Meeders, Fasth, Morgan, Vellodi, Hale, Bujan, Thomas, Cavazzana-Calvo, Wijdenes, Fischer: "Bone marrow transplantation from genetically HLA-nonidentical donors in children with fatal inherited disorders excluding severe combined immunodeficiencies: use of two monoclonal antibodies to prevent graft rejection." dans: Pediatrics, Vol. 98, Issue 3 Pt 1, pp. 420-8, (1996) (PubMed).

    Racadot, Milpied, Bordigoni, Cahn, Plouvier, Lioure, Lutz, Wijdenes, Herve: "Sequential use of three monoclonal antibodies in corticosteroid-resistant acute GVHD: a multicentric pilot study including 15 patients." dans: Bone marrow transplantation, Vol. 15, Issue 5, pp. 669-77, (1995) (PubMed).

  • Antigène

    CD2

    Autre désignation

    CD2

    Sujet

    LFA-2

    Poids moléculaire

    50 kDa
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