RAB17 anticorps (AA 101-200)

N° du produit ABIN1385185

Cet anticorps Lapin Polyclonal détecte spécifiquement RAB17 dans WB, ELISA, IF (cc), IF (p), IHC (p), ICC et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour RAB17 anticorps (AA 101-200) (ABIN1385185)

Antigène: RAB17 (RAB17, Member RAS Oncogene Family (RAB17))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB17 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-RAB17 anticorps

Épitope: AA 101-200

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Rab17

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur RAB17

Antigène: RAB17 (RAB17, Member RAS Oncogene Family (RAB17))

Autre désignation: Rab17

Sujet:

Synonyms: Rab 17, Rab17, RAB17 member RAS oncogene family, RAB17_HUMAN, Ras related protein Rab 17, Ras related protein Rab17, Ras-related protein Rab-17, FLJ12538, OTTHUMP00000164417, OTTHUMP00000202805.

Background: Rab17 belongs to the Rab family of small Ras-like GTPases. It is specifically expressed in epithelial cells and is upregulated during cell polarization. Immunofluorescence staining studies indicate that Rab17 is associated with the perinuclear recycling endosome in nonpolarized epithelial cells and with the apical recycling endosome in polarized epithelial cells. The function of Rab17 remains unclear. Reports of Rab17 colocalization with internalized IgA in the apical endosome suggest that it may regulate receptor-mediated transcytosis. Rab17 has also been shown to regulate melanocytic filopodia formation and melanosome trafficking. siRNA knockdown of Rab17 in melanoma cells induces melanosome accumulation in the cell periphery.