CCRN4L anticorps (AA 231-330)
Aperçu rapide pour CCRN4L anticorps (AA 231-330) (ABIN1385748)
Antigène
Voir toutes CCRN4L AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 231-330
-
Réactivité croisée
- Souris, Rat
-
Homologie
- Human
-
Purification
- Purified by Protein A.
-
Immunogène
- KLH conjugated synthetic peptide derived from human Nocturnin
-
Isotype
- IgG
-
-
-
-
Indications d'application
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 μg/μL
-
Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
Agent conservateur
- ProClin
-
Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
Date de péremption
- 12 months
-
-
- CCRN4L (CCR4 Carbon Catabolite Repression 4-Like (CCRN4L))
-
Autre désignation
- Nocturnin
-
Sujet
-
Synonyms: CCR4 carbon catabolite repression 4 like S. cerevisiae, CCR4 protein homolog, CCRN4L, NOC, NOCT_HUMAN.
Background: Nocturnin is a 431 amino acid circadian deadenylase protein that is expressed in a broad range of tissues with greatest abundance in the liver, kidney and testis. Nocturnin plays a role in circadian regulation as well as diet-induced obesity. The mRNA abundance of Nocturnin exhibits circadian rhythmicity, peaking after dusk in photoreceptors, spleen, heart, kidney and liver. Nocturnin is thought to be responisble for turning off genes that are involved in circadian regulation. In Xenopus retinal photoreceptor cells, the rhythmic regulation of Nocturnin is thought to be controlled by phosphorylated CREB. Mice lacking Nocturnin remain lean on high fat diets with a reduction in visceral fat, which suggests that this protein may also be responsible for lipid metabolism and fat storage.
-
ID gène
- 25819
-
Pathways
- Ribonucleoprotein Complex Subunit Organization
Antigène
-