ENTPD2 anticorps (AA 401-495)

N° du produit ABIN1385820

Cet anticorps anti-ENTPD2 est un anticorps Lapin Polyclonal détectant ENTPD2 dans WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) et ICC. Adapté pour Rat. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour ENTPD2 anticorps (AA 401-495) (ABIN1385820)

Antigène: ENTPD2 (Ectonucleoside Triphosphate diphosphohydrolase 2 (ENTPD2))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ENTPD2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Détail du produit anti-ENTPD2 anticorps

Épitope: AA 401-495

Réactivité croisée: Rat

Homologie: Human,Mouse,Cow,Sheep,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ENTPD2/CD39L1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-ENTPD2 (ABIN1385820)

Hwang, Dornbos, Steidemann, Dunivin, Rizzo, LaPres: "Mitochondrial-targeted aryl hydrocarbon receptor and the impact of 2,3,7,8-tetrachlorodibenzo-p-dioxin on cellular respiration and the mitochondrial proteome." dans: Toxicology and applied pharmacology, (2016) (PubMed).

Détails sur ENTPD2

Antigène: ENTPD2 (Ectonucleoside Triphosphate diphosphohydrolase 2 (ENTPD2))

Autre désignation: ENTPD2/CD39L1

Sujet:

Synonyms: CD39 antigen like 1, CD39 antigen-like 1, CD39 like1, CD39L1, CD39like1, ecto ATP diphosphohydrolase 2, ecto ATPase 2, ecto ATPDase 2, Ecto-ATP diphosphohydrolase 2, Ecto-ATPase 2, Ecto-ATPDase 2, ectoATPase 2, ectoATPDase 2, Ectonucleoside triphosphate diphosphohydrolase 2, ENTP2_HUMAN, Entpd2, NTPDase 2, NTPDase2.

Background: CD39, also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENP1), is an integral membrane glycoprotein that acts as an extracellular nucleotide-hydrolyzing enzyme. CD39 inhibits ADP-induced platelet aggregation by hydrolyzing ADP to AMP and ultimately generating adenosine. Intracellular CD39 undergoes glycosylation at 6 N-glycosylation sites and translocates to the membrane in order to be an active enzyme. CD39L1 is a 495 amino acid multi-pass membrane protein that requires calcium and magnesium cofactors to hydrolyze ATP and other nucleotides in the regulation of purigenic neurotransmission. CD39L1 is expressed in kidney, colon, heart, testis, pancreas, brain, prostate, skeletal muscle, small intestine and ovaries. There are two isoforms of CD39L1 that are produced as a result of alternative splicing events.