Osteocalcin anticorps (AA 21-100)

N° du produit ABIN1385851

Cet anticorps Lapin Polyclonal détecte spécifiquement Osteocalcin dans WB, ELISA, ICC, IHC (p), IHC (fro), IF (cc) et IF (p). Il présente une réactivité envers Humain, Rat, Souris et Chien et a été mentionné dans 3+ publications.

Aperçu rapide pour Osteocalcin anticorps (AA 21-100) (ABIN1385851)

Antigène: Osteocalcin (BGLAP)

Reactivité: Humain, Rat, Souris, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Osteocalcin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-Osteocalcin anticorps

Épitope: AA 21-100

Réactivité croisée: Chien, Humain, Souris, Rat

Homologie: Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Osteocalcin

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Osteocalcin (ABIN1385851)

Jiang, Zhou, Huang, Wu, Huang, Liang, Liu, Zheng, Zhao: "Andrographolide Exerts Pro-Osteogenic Effect by Activation of Wnt/β-Catenin Signaling Pathway in Vitro." dans: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 36, Issue 6, pp. 2327-39, (2016) (PubMed).

Li, Zhou, Wang, Yang, Ding, Zhou: "Controlled dual delivery of BMP-2 and dexamethasone by nanoparticle-embedded electrospun nanofibers for the efficient repair of critical-sized rat calvarial defect." dans: Biomaterials, Vol. 37, pp. 218-29, (2015) (PubMed).

Ding, Li, Liu, Yang, Zhou, Zhou: "A nano-micro alternating multilayer scaffold loading with rBMSCs and BMP-2 for bone tissue engineering." dans: Colloids and surfaces. B, Biointerfaces, Vol. 133, pp. 286-95, (2015) (PubMed).

Détails sur Osteocalcin

Antigène: Osteocalcin (BGLAP)

Autre désignation: Osteocalcin

Sujet:

Synonyms: Osteocalcin, Bone Gla protein, BGP, Gamma-carboxyglutamic acid-containing protein, BGLAP

Background: Osteocalcin belongs to the osteocalcin/matrix Gla protein family and constitutes 1 to 2 % of the total bone protein. It is a 49 amino acid single chain vitamin K dependent protein, made by osteoblasts, and is a major component of the noncollagenous bone matrix. Post translational modification by a vitamin K dependent carboxylase produces three gamma carboxyglutamic acid residues at positions 17, 21 and 24, giving it a high affinity for calcium. It also binds strongly to apatite.

ID gène: 632

UniProt: P02818