MAGOH anticorps (AA 51-146)

N° du produit ABIN1385905

Cet anticorps Lapin Polyclonal détecte spécifiquement MAGOH dans ELISA, IF (cc), IF (p), IHC (p), IHC (fro) et ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour MAGOH anticorps (AA 51-146) (ABIN1385905)

Antigène: MAGOH (Mago-Nashi Homolog (MAGOH))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAGOH est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Détail du produit anti-MAGOH anticorps

Épitope: AA 51-146

Homologie: Human,Mouse,Rat,Cow,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MAGOH

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur MAGOH

Antigène: MAGOH (Mago-Nashi Homolog (MAGOH))

Autre désignation: MAGOH

Sujet:

Synonyms: Mago nashi homolog proliferation associated Drosophila, Mago nashi protein homolog , magoh, MGN_HUMAN, Protein mago nashi homolog.

Background: MAGOH, the human homolog of Drosophila mago nashi, is required for embryo development. MAGOH is ubiquitously expressed in adult tissues. It has an unusual structure consiting of an extremely flat, six-stranded anti-parallel _ sheet packed next to two helices. MAGOH interacts with the Y14 protein to form a complex that plays a crucial role in postsplicing processing (including nuclear export and cytoplasmic localization of the mRNA) and in the nonsense-mediated mRNA decay (NMD) surveillance process. The MAGOH-Y14 complex remains persistently associated in the same position on the mRNA after its export to the cytoplasm and requires translation of the mRNA for removal. This complex may illustrate the mechanism of the pre-mRNA splicing machinery for forming a stable exon-exon junction complex-mRNA at splice junctions.