DPH2 anticorps (AA 401-489)

N° du produit ABIN1385915

L’anticorps Lapin Polyclonal anti-DPH2 a été validé pour WB, ELISA, IHC (p), IF (cc), IF (p) et IHC (fro). Il convient pour détecter DPH2 dans des échantillons de Humain.

Aperçu rapide pour DPH2 anticorps (AA 401-489) (ABIN1385915)

Antigène: DPH2 (Diphthamide Biosynthesis Protein 2 (DPH2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DPH2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-DPH2 anticorps

Épitope: AA 401-489

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DPH2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur DPH2

Antigène: DPH2 (Diphthamide Biosynthesis Protein 2 (DPH2))

Autre désignation: Dph2

Sujet:

Synonyms: Diphthamide biosynthesis like protein 2, Diphthamide biosynthesis protein 2, Diphthamide biosynthesis protein 2 homolog like 2, Diphthamide biosynthesis protein 2 homolog-like 2, Diptheria toxin resistance protein required for diphthamide biosynthesis like 2, Diptheria toxin resistance protein required for diphthamide biosynthesis like 2 S. cerevisiae , DPH 2, DPH2, DPH2 homolog, DPH2 homolog S. cerevisiae, DPH2 like 2, DPH2 like 2 S. cerevisiae, DPH2-like 2, DPH2_HUMAN, DPH2L2, HsDph2, OTTHUMP00000010007, Protein DPH2 homolog.

Background: DPH2 (diphthamide biosynthesis protein 2), also known as DPH2L2, is a 489 amino acid protein that shows strong expression in skeletal muscle, moderate expression in heart, small intestine, liver, pancreas, testis and colon, and lesser expression in brain, placenta, kidney, spleen, thymus, prostate, ovary and lymphocytes. DPH2 interacts with DPH1 and, functioning together as a dimer or multimer, DPH1 and DPH2 may participate in diphthamide biosynthesis. Diphthamide is a posttranslationally modified histidine residue which occurs in EF-2 (elongation factor 2) and targets diphtheria toxin ADP-ribosylation. The loss of DPH2 in Saccharomyces cerevisiae is believed to suppress zymocicity. Two transcript variants encoding different isoforms have been found for this gene.Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2.Tissue specificity:Strongly expressed in skeletal muscle. Moderately expressed in heart, small intestine, liver, pancreas, testis and colon. Weakly expressed in brain, placenta, kidney, speen, thymus, prostate, ovary and lymphocytes.

ID gène: 1802