TNRC6B anticorps (AA 25-70)

N° du produit ABIN1385992

Cet anticorps Lapin Polyclonal détecte spécifiquement TNRC6B dans WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) et ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour TNRC6B anticorps (AA 25-70) (ABIN1385992)

Antigène: TNRC6B (Trinucleotide Repeat Containing 6B (TNRC6B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNRC6B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Détail du produit anti-TNRC6B anticorps

Épitope: AA 25-70

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TNRC6B

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur TNRC6B

Antigène: TNRC6B (Trinucleotide Repeat Containing 6B (TNRC6B))

Autre désignation: TNRC6B

Sujet:

Synonyms: KIAA1093, TNRC 6B, Trinucleotide repeat containing 6B, Trinucleotide repeat containing gene 6B protein, TNR6B_HUMAN.

Background: TNRC6B is a 1,723 amino acid protein that exists as two alternatively spliced isoforms and is thought to be involved in mRNA cleavage events. Expressed ubiquitously, TNRC6B contains one glycine/tryptophan (GW)-rich N-terminal domain, one central glutamine-rich region and one C-terminal RNA recognition motif and is encoded by a gene that maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway