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RNF180 anticorps

RNF180 Reactivité: Humain, Souris, Rat WB, IF (p), IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1386111
  • Antigène Voir toutes RNF180 Anticorps
    RNF180 (Ring Finger Protein 180 (RNF180))
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 31
    • 2
    Lapin
    Clonalité
    • 31
    • 2
    Polyclonal
    Conjugué
    • 9
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RNF180 est non-conjugé
    Application
    • 33
    • 14
    • 14
    • 12
    • 5
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human RNF180
    Isotype
    IgG
    Top Product
    Discover our top product RNF180 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    RNF180 (Ring Finger Protein 180 (RNF180))
    Autre désignation
    RNF180 (RNF180 Produits)
    Synonymes
    anticorps 3110001E11Rik, anticorps Rines, anticorps ring finger protein 180, anticorps Rnf180, anticorps RNF180
    Sujet

    Synonyms: Rines, 3110001E11Rik, MGC120326, MGC120328, MGC188174, rCG_44674, Ring finger protein 180.

    Background: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF180 (ring finger protein 180), also known as Rines, is a 592 single-pass membrane protein that contains a single RING-type zinc finger. Expressed as three alternatively spliced isoforms, RNF180 is well conserved among vertebrates. RNF180 is expressed in brain, kidney, testis and uterus and localizes to the endoplasmic reticulum. RNF180 is an E3 ubiquitin ligase involved in the ubiquitin-proteasome pathway. RNF180 is encoded by a gene located on human chromosome 5, which contains 181 million base pairs and comprises nearly 6 % of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm, or of chromosome 5 altogether, is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

    ID gène
    285671
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