ITM2C anticorps (AA 3-88)

N° du produit ABIN1386181

Cet anticorps Lapin Polyclonal détecte spécifiquement ITM2C dans WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) et ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour ITM2C anticorps (AA 3-88) (ABIN1386181)

Antigène: ITM2C (Integral Membrane Protein 2C (ITM2C))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITM2C est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Détail du produit anti-ITM2C anticorps

Épitope: AA 3-88

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ITM2C

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur ITM2C

Antigène: ITM2C (Integral Membrane Protein 2C (ITM2C))

Autre désignation: ITM2C

Sujet:

Synonyms: BRI3, BRICD2C, BRICHOS domain containing 2C, Cerebral protein 14, CT-BRI3, E25, E25C , Integral membrane protein 2C, Integral membrane protein 3, Itm2c, ITM2C_HUMAN, ITM3 antibodyNPD018, Transmembrane protein BRI3.

Background: Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.

ID gène: 81618

UniProt: Q9NQX7