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AACS anticorps (AA 182-228)

AACS Reactivité: Humain WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1386192
  • Antigène Voir toutes AACS Anticorps
    AACS (Acetoacetyl-CoA Synthetase (AACS))
    Épitope
    • 14
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 182-228
    Reactivité
    • 33
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 32
    • 1
    Lapin
    Clonalité
    • 33
    Polyclonal
    Conjugué
    • 13
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp AACS est non-conjugé
    Application
    • 27
    • 12
    • 12
    • 12
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human AACS
    Isotype
    IgG
    Top Product
    Discover our top product AACS Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    AACS (Acetoacetyl-CoA Synthetase (AACS))
    Autre désignation
    AACS/ACSF1 (AACS Produits)
    Synonymes
    anticorps sur-5, anticorps An08g04090, anticorps AO090001000376, anticorps ACSF1, anticorps SUR-5, anticorps 2210408B16Rik, anticorps SUR5, anticorps zgc:56105, anticorps acetoacetyl-CoA synthetase, anticorps bll4282, anticorps acetoacetyl-coa synthetase, anticorps acetoacetate--CoA ligase, anticorps acetoacetate-CoA ligase, anticorps Acetoacetyl-CoA synthetase, anticorps AACS, anticorps LOC590598, anticorps aacs, anticorps bll4282, anticorps Pfl01_3080, anticorps h16_A2860, anticorps Mflv_1473, anticorps ANI_1_594074, anticorps Pput_2653, anticorps VIBHAR_RS20435, anticorps AOR_1_648164, anticorps CC1G_04522, anticorps LACBIDRAFT_230952, anticorps PLES_33261, anticorps PA1997, anticorps OB0504, anticorps CBU_0766, anticorps acsA2, anticorps Sde_0006, anticorps Plav_1154, anticorps AZC_2243, anticorps SGR_RS30655, anticorps Aacs, anticorps sur-5
    Sujet

    Synonyms: Acetoacetyl-CoA synthetase, ACSF1, Acyl-CoA synthetase family member 1, Protein sur-5 homolog, AACS_HUMAN.

    Background: ACSF1 is a 672 amino acid protein belonging to the ATP-dependent AMP-binding enzyme family. Encoded by a gene that maps to human chromosome 12q24.31, ACSF1 is highly expressed in kidney, heart and brain, and shows similar neural expression as HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase). Existing as three alternatively spliced isoforms, ACSF1 participates in ATP binding, ligase activity, acetoacetate-CoA ligase activity and nucleotide binding. The ACSF1 promoter is a known PPAR?target gene, with the nuclear receptor recruited to the ACSF1 promoter by direct interaction with stimulating protein-1 (Sp1). ACSF1 activates acetoacetate and is highly regulated by modulators that affect HMGCR and cholesterol biosynthesis.

    ID gène
    65985
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis
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