WT1 anticorps (AA 301-400)

N° du produit ABIN1386293

L’anticorps Lapin Polyclonal anti-WT1 a été validé pour FACS, WB, ELISA, IHC (p), IF (cc), IF (p) et IHC (fro). Il convient pour détecter WT1 dans des échantillons de Humain, Rat, Souris et Boeuf (Vache). Il y a 1 publication disponible.

Aperçu rapide pour WT1 anticorps (AA 301-400) (ABIN1386293)

Antigène: WT1 (Wilms Tumor 1 (WT1))

Reactivité: Humain, Rat, Souris, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WT1 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-WT1 anticorps

Épitope: AA 301-400

Réactivité croisée: Boeuf (Vache), Humain, Souris, Rat

Homologie: Dog,Cow,Sheep,Pig,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Wilms Tumor Protein

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-WT1 (ABIN1386293)

Xiao, Guan, Nie, Wang, Sun, He, Huang, Zhang, Yang, Wang, Zhao: "Rapamycin promotes podocyte autophagy and ameliorates renal injury in diabetic mice." dans: Molecular and cellular biochemistry, Vol. 394, Issue 1-2, pp. 145-54, (2014) (PubMed).

Détails sur WT1

Antigène: WT1 (Wilms Tumor 1 (WT1))

Autre désignation: Wilms Tumor Protein

Sujet:

Synonyms: GUD, AWT1, WAGR, WT33, NPHS4, WIT-2, EWS-WT1, Wilms tumor protein, WT1

Background: Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.

Poids moléculaire: 55kDa

ID gène: 7490

UniProt: P19544

Pathways: Tube Formation