5ht6 Receptor/Sr-6 (AA 51-150) anticorps

N° du produit ABIN1386313

Cet anticorps Lapin Polyclonal détecte spécifiquement 5ht6 Receptor/Sr-6 dans ELISA, ICC, IF (cc), IF (p), IHC (fro), IHC (p) et WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour 5ht6 Receptor/Sr-6 (AA 51-150) anticorps (ABIN1386313)

Antigène: 5ht6 Receptor/Sr-6

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Application: ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Détail du produit

Épitope: AA 51-150

Homologie: Human,Mouse,Rat,Dog,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human 5HT6 Receptor/SR-6

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: 5ht6 Receptor/Sr-6

Sujet:

Synonyms: 5 HT 6, 5 HT6, 5 hydroxytryptamine 6 receptor, 5 hydroxytryptamine receptor 6, 5-HT-6, 5-HT6, 5-hydroxytryptamine receptor 6, 5HT 6, 5HT6R_HUMAN, HTR 6, HTR6, Serotonin receptor 6.

Background: Serotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it is predominantly expressed in the gut, platelets and central nervous system (CNS). In the CNS, serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors. SR-3 is a ligand-gated ion channel, whereas all other known serotonin receptor subtypes are G protein-coupled receptors. Human SR-6 is one of the latest cloned receptors among the known SR receptors. ISR-6 is expressed in the limbic region, which is involved in the control of mood and emotion and in nervous system diseases such as depression and Alzheimer's disease. The cellular mechanisms of SR-6 have not been clearly elucidated.