ADRA2C anticorps (AA 21-120)
Aperçu rapide pour ADRA2C anticorps (AA 21-120) (ABIN1386323)
Antigène
Voir toutes ADRA2C AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 21-120
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Réactivité croisée
- Humain, Souris
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Homologie
- Rat,Dog,Pig
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human ADRA2C/alpha 2C Adrenergic Receptor
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Isotype
- IgG
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Indications d'application
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ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))
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Autre désignation
- ADRA2C/alpha 2C Adrenergic Receptor
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Sujet
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Synonyms: Adra 2c, Adra 2c, ADRA2C, ADRA2C, ADRA2L2, ADRA2L2, ADRA2RL2, ADRA2RL2, ADRARL2, ADRARL2, Adrenergic alpha 2C receptor, Adrenoceptor alpha 2C, Alpha 2C adrenergic receptor, Alpha 2C adrenergic receptor subtype C4, Alpha 2C adrenoceptor, Alpha 2C adrenoreceptor, Alpha 2CAR, alpha2 AR C4, alpha2 AR C4, alpha2 C4, alpha2 C4, alpha2C, alpha2C, ALPHA2CAR, alpha2cii-adrenergic receptor, Subtype alpha2 C4, Subtype alpha2 C4, ADA2C_HUMAN.
Background: alpha2C-adrenergic receptors (alpha2C-AR) regulate neurotransmitter release from sympathetic nerves in the heart, and from adrenergic neurons in the central nervous system. alpha2C-AR can influence Parkinson?s disease, panic disorders, and Huntington disease (HD) progression. A genetic variant in the alpha2C-AR coding region (Del322-325) renders the receptor partially uncoupled from Gi, and is a contributing risk factor for heart failure. alpha2C-AR transcripts are present in rat muscle, heart, pancreas, and kidney.
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Pathways
- EGFR Signaling Pathway, cAMP Metabolic Process
Antigène
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