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Fascin 3 anticorps (AA 401-498)

Cet anticorps anti-Fascin 3 est un anticorps Lapin Polyclonal détectant Fascin 3 dans WB, ELISA, IHC (p), ICC, IF (cc), IF (p) et IHC (fro). Adapté pour Humain.
N° du produit ABIN1386492

Aperçu rapide pour Fascin 3 anticorps (AA 401-498) (ABIN1386492)

Antigène

Voir toutes Fascin 3 (FSCN3) Anticorps
Fascin 3 (FSCN3)

Reactivité

  • 19
  • 8
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Humain

Hôte

  • 19
Lapin

Clonalité

  • 19
Polyclonal

Conjugué

  • 14
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Fascin 3 est non-conjugé

Application

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Épitope

    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 401-498

    Homologie

    Human,Mouse,Rat,Dog,Sheep,Pig,Horse

    Purification

    Purified by Protein A.

    Immunogène

    KLH conjugated synthetic peptide derived from human Fascin-3

    Isotype

    IgG
  • Indications d'application

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Date de péremption

    12 months
  • Antigène

    Fascin 3 (FSCN3)

    Autre désignation

    FSCN3/Fascin-3

    Sujet

    Synonyms: Fascin testis, Fascin 3, Fascin homolog 3 actin bundling protein testicular Strongylocentrotus purpuratus , Fascin homolog 3 actin bundling protein testicular, Fascin3, FSCN 3, FSCN3, MGC94950, Testis fascin, FSCN3_HUMAN.

    Background: Cell adhesion to extracellular matrix is an important physiological stimulus for organization of the Actin-based cytoskeleton. Adhesion to the matrix glycoprotein Thrombospondin 1 triggers the sustained formation of F-Actin microspikes that contain the Actin-bundling protein Fascin. These structures are also implicated in cell migration, which may be an important function of Thrombospondin 1 in tissue remodelling and wound repair. Fascin bundles Actin microfilaments within dynamic cellular structures such as microspikes, stress fibers and membrane ruffles. Fascin could serve as a prognostic factor for abnormal ovarian epithelial pathology and could be a novel target for the treatment of ovarian cancer. Fascin, an Actin-bundling protein, identifies dendritic cells in the blood and in tissues.

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