Lap1/Densin180 (AA 601-700) anticorps

N° du produit ABIN1386526

Cet anticorps Lapin Polyclonal détecte spécifiquement Lap1/Densin180 dans ELISA, ICC, IF (cc), IF (p), IHC (fro) et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Lap1/Densin180 (AA 601-700) anticorps (ABIN1386526)

Antigène: Lap1/Densin180

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Application: ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit

Épitope: AA 601-700

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Densin180

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Lap1/Densin180

Sujet:

Synonyms: Densin 180, Densin, Densin-180, densin180, DKFZp686I1147, KIAA1365, Lamin associated polypeptide 1, LAP 1, Leucine rich repeat containing 7, Leucine rich repeat containing protein 7, Leucine-rich repeat-containing protein 7,Lrrc 7, Lrrc7, LRRC7_HUMAN, MGC144918, OTTHUMP00000065336, OTTHUMP00000065337,OTTHUMP00000065338, Protein Lap 1, Protein lap1.

Background: Densin-180 is a synaptic transmembrane protein that is tightly associated with the postsynaptic density in CNS neurons and is postulated to function as a synaptic adhesion molecule. Densin-180 is a brain-specific momber of the O-sialoglycoprotein family which is highly concentrated at synapses along dendrites. The sequence of densin-180 contains 17 leucine-rich repeats, a sialomucin domain, an apparent transmembrane domain, and a PDZ (PSD-95, DIg, Z0-1) domain. The PDZ domain contributes to its binding to a-actinin. The intracellular portion of densin-180, CaMKIIa, interacts with a-actinin at distinct binding sites and, together, they form a ternary complex stabilized by multiple interactions.

ID gène: 57554

UniProt: Q96NW7