Synaptojanin 1 anticorps (AA 481-580)

N° du produit ABIN1386543

Cet anticorps anti-Synaptojanin 1 est un anticorps Lapin Polyclonal détectant Synaptojanin 1 dans ELISA, IF (cc), IF (p), IHC (fro), ICC et IHC (p). Adapté pour Rat.

Aperçu rapide pour Synaptojanin 1 anticorps (AA 481-580) (ABIN1386543)

Antigène: Synaptojanin 1 (SYNJ1)

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Synaptojanin 1 est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Synaptojanin 1 anticorps

Épitope: AA 481-580

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Synaptojanin/INPP5G

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur Synaptojanin 1

Antigène: Synaptojanin 1 (SYNJ1)

Autre désignation: Synaptojanin 1

Sujet:

Synonyms: 5-trisphosphate 5-phosphatase 1, Inositol 5' phosphatase, INPP 5G, INPP5G, KIAA0910, Polyphosphoinositide phosphatase, Synaptic inositol 1 4 5 trisphosphate 5 phosphatase 1, Synaptic inositol 145 trisphosphate 5 phosphatase 1, Synaptic inositol-1 antibody Synaptic inositol-145-trisphosphate 5-phosphatase 1, Synaptojanin 1, Synaptojanin 1 polyphosphoinositide phosphatase, Synaptojanin-1, Synaptojanin1, Synj 1, Synj1, SYNJ1_HUMAN.

Background: The inositol polyphosphate 5-phosphatases selectively remove the phosphate from the 5-position of various phosphatidylinositols, which generate second messengers in response to extracellular signals. Synaptojanins are characterized by an N-terminal SAC1-like sequence, a central 5-phosphate domain, and a unique C-terminal sequence and have been shown to use phosphatidylinositol 4,5-bisphosphate as a substrate. Synaptojanins exist as two isoforms, synaptojanin 1 and 2, which differ in the C-terminal domain, and each isoform has multiple variants produced by alternative splicing. Synaptojanin 1 is expressed as two major forms: the shorter is found in brain while the longer is expressed in peripheral tissues. Eight splice variants of synaptojanin 2 have been detected, including a brain specific isoform. Synaptojanins are thought to participate in the endocytosis of synaptic vesicles and the regulation of the actin cytoskeleton.

ID gène: 8867

Pathways: Inositol Metabolic Process, Synaptic Vesicle Exocytosis