KCNT2 anticorps (AA 51-150)

N° du produit ABIN1386737

L’anticorps Lapin Polyclonal anti-KCNT2 a été validé pour IF (cc), IF (p), ELISA, IHC (p), ICC et IHC (fro). Il convient pour détecter KCNT2 dans des échantillons de Humain.

Aperçu rapide pour KCNT2 anticorps (AA 51-150) (ABIN1386737)

Antigène: KCNT2 (Potassium Channel, Subfamily T, Member 2 (KCNT2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNT2 est non-conjugé

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-KCNT2 anticorps

Épitope: AA 51-150

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human KCNT2

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur KCNT2

Antigène: KCNT2 (Potassium Channel, Subfamily T, Member 2 (KCNT2))

Autre désignation: KCNT2

Sujet:

Synonyms: KCa4.2, Potassium channel, subfamily T, member 2, Sequence like an intermediate conductance potassium channel subunit, SLICK, SLO2.1, Sodium and chloride activated ATP sensitive potassium channel, Sodium and chloride activated ATP sensitive potassium channel Slo2.1, KCNT2_HUMAN.

Background: Voltage-gated K+ channels in the plasma membrane are important regulators of electrical signaling, controlling the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. KCNT2 is a 1,135 amino acid multi-pass transmembrane protein belonging to the potassium channel family (calcium-activated subfamily) of proteins. KCNT2 produces rapidly activating outward rectifier potassium currents in reponse to high intracellular sodium and chloride levels. Its channel activity is inhibited by ATP, inhalation anesthetics, such as isoflourane, and upon stimulation of G-protein coupled receptors, such as mAChR M1 and GluR-1. There are four isoforms of KCNT2 that are produced as a result of alternative splicing events.