ZNF281 anticorps (AA 802-895)
Aperçu rapide pour ZNF281 anticorps (AA 802-895) (ABIN1386745)
Antigène
Voir toutes ZNF281 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 802-895
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Réactivité croisée
- Humain
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Homologie
- Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human ZNF281
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- ZNF281 (Zinc Finger Protein 281 (ZNF281))
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Autre désignation
- ZNF281
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Sujet
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Synonyms: Zfp281, GC box binding zinc finger protein 1, GC-box-binding zinc finger protein 1, GZP1, Transcription factor ZBP-99, ZBP 99, ZBP99, zfp281, Zinc finger DNA binding protein 99, Zinc finger DNA-binding protein 99, Zinc Finger Protein 281, ZN281_HUMAN, ZNF281, ZNP 99, ZNP 99 transcription factor, ZNP99.
Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF281, also known as GC-box-binding zinc finger protein 1, ZBP-99 or ZNP-99 (zinc finger DNA-binding protein 99), is a zinc finger protein that belongs to the Kr_ppel C2H2-type zinc finger protein family. It is expressed ubiquitously at low levels with predominant expression in kidney, liver, lymphocytes and placenta. ZNF281 localizes to the nucleus and contains four C2H2-type zinc fingers. ZNF281 plays a role in repressing the transcription of a variety of genes including Gastrin and ODC (ornithine decarboxylase). In particular, ZNF281 functions by binding to the G-rich box in the enhancer region of the gene. Upon DNA damage, ZNF281 may become phosphorylated by Atm or ATR.
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ID gène
- 23528
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Pathways
- Embryonic Body Morphogenesis
Antigène
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