MYF5 anticorps (pSer49)

N° du produit ABIN1386790

Cet anticorps Lapin Polyclonal détecte spécifiquement MYF5 dans WB, ELISA, IHC (p), IF (cc), IF (p) et IHC (fro). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour MYF5 anticorps (pSer49) (ABIN1386790)

Antigène: MYF5 (Myogenic Factor 5 (MYF5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYF5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-MYF5 anticorps

Épitope: pSer49

Homologie: Human,Mouse,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human MYF5 around the phosphorylation site of Ser49

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur MYF5

Antigène: MYF5 (Myogenic Factor 5 (MYF5))

Autre désignation: Myf5

Sujet:

Synonyms: Myf5 phospho S49, Myf5 phospho Ser49, p-Myf5phospho S49, p-Myf5phospho Ser49, Myf-5 bHLHc2, Class C basic helix loop helix protein 2, Class C basic helix-loop-helix protein 2, Myf 5, Myf-5, Myf5, MYF5_HUMAN, Myogenic factor 5.

Background: Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development include Myo D, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin). Of interest, most muscle cells express either Myo D or Myf-5 in the committed state, but when induced to differentiate, all turn on expression of myogenin. Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes.

ID gène: 4617

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development