DSPP anticorps

N° du produit ABIN1386864

Cet anticorps anti-DSPP est un anticorps Lapin Polyclonal détectant DSPP dans IF (p) et IHC (p). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour DSPP anticorps (ABIN1386864)

Antigène: DSPP (Dentin Sialophosphoprotein (DSPP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DSPP est non-conjugé

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-DSPP anticorps

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DSPP/Dentin phosphophoryn

Isotype: IgG

Information d'application

Indications d'application: IHC-P: (1:100-500), IF(IHC-P): (1:50-200)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur DSPP

Antigène: DSPP (Dentin Sialophosphoprotein (DSPP))

Autre désignation: DSPP

Sujet:

Synonyms: Dentin phosphophoryn, Dentin phosphoprotein, dentin phosphoryn, Dentin sialophosphoprotein, Dentin sialophosphoprotein precursor, Dentin sialoprotein, dentinogenesis imperfecta 1, DFNA39, DGI1, DMP3, DPP, DSP, Dspp, DSPP_HUMAN, DTDP2.

Background: DSPP may be an important factor in dentinogenesis. DSPP may bind high amount of calcium and facilitate initial mineralization of dentin matrix collagen as well as regulate the size and shape of the crystals.The dentin sialophosphoprotein (DSPP) gene encodes two major noncollagenous dentin matrix proteins: dentin sialoprotein, known as DSP, and dentin phosphoprotein, known as phosphophoryn or DPP. The DSPP gene maps to human chromosome 4 and yields a 4.6 kb transcript containing 5 exons, with exons 1-4 encoding for DSP and exon 5 encoding for both the C-terminus of DSP and the full length DPP. DPP and DSP are acidic proteins that represent about 50 % of the noncollagenous proteins in the dentin extracellular matrix of teeth. The DSPP gene is a likely candidate gene for the genetic diseases associated with abnormal dentin formation such as dentinogenesis imperfecta type II and dentin dysplasia type II. DPP may bind large amounts of calcium and may facilitate initial mineralization of dentin matrix collagen as well as regulate the size and shape of the crystals.

ID gène: 1834