RNF216 anticorps

N° du produit ABIN1386955

Cet anticorps Lapin Polyclonal détecte spécifiquement RNF216 dans IF (p) et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour RNF216 anticorps (ABIN1386955)

Antigène: RNF216 (Ring Finger Protein 216 (RNF216))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF216 est non-conjugé

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-RNF216 anticorps

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TRIAD3

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur RNF216

Antigène: RNF216 (Ring Finger Protein 216 (RNF216))

Autre désignation: TRIAD3

Sujet:

Synonyms: E3 ubiquitin ligase TRIAD3, ring finger protein 216, RNF216, Triad domain-containing protein 3, U7I1, UBCE7IP1, Ubiquitin conjugating enzyme 7 interacting protein 1, UiP83, ZIN, Zinc finger protein inhibiting NF kappa B, RN216_HUMAN.

Background: The TRIAD3 gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known.

ID gène: 54476