SLFN14 anticorps

N° du produit ABIN1386973

Détail du produit anti-SLFN14 anticorps

Antigène: SLFN14 (Schlafen Family Member 14 (SLFN14))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLFN14 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SLFN14

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur SLFN14

Antigène: SLFN14 (Schlafen Family Member 14 (SLFN14))

Autre désignation: SLFN14 (SLFN14 Produits)

Synonymes: anticorps LRRGT00163, anticorps Gm20, anticorps Slfn14-ps, anticorps schlafen family member 14, anticorps protein SLFN14, anticorps schlafen family member 11, anticorps schlafen 14, anticorps Slfn14, anticorps LOC491140, anticorps SLFN14, anticorps SLFN11, anticorps LOC100021434, anticorps LOC100358198

Sujet:

Synonyms: Schlafen family member 14, SLFN14, SLN14_HUMAN.

Background: Schlafen family members are preferentially expressed in lymphoid tissues and are differentially regulated during thymocyte maturation. Schlafen proteins function as suppressors of cell growth and are thought to play a role in the maintenance of T cell quiescence. The prototype member of the Schlafen family, Slfn1, is transcriptionally unregulated during thymocyte positive selection, and the induction of Slfn1 induces a G0/G1 arrest, suggesting that Slfn1 participates in the regulation of cell cycle and potentially acts as a determining factor for apoptosis. These proteins all contain a largely conserved core domain within the center of the sequence, and yet they are substantially diversified at the N terminus. Slfn14 (Schlafen family member 14) is a 912 amino acid protein belonging to the Schlafen family. Slfn14 exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 17q12.

ID gène: 342618

UniProt: P0C7P3