DCAF12 anticorps

N° du produit ABIN1387059

Détail du produit anti-DCAF12 anticorps

Antigène: DCAF12 (DDB1 and CUL4 Associated Factor 12 (DCAF12))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCAF12 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DCAF12/WDR40A

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur DCAF12

Antigène: DCAF12 (DDB1 and CUL4 Associated Factor 12 (DCAF12))

Autre désignation: DCAF12 (DCAF12 Produits)

Synonymes: anticorps CT102, anticorps KIAA1892, anticorps TCC52, anticorps WDR40A, anticorps 1500001L20Rik, anticorps 5830424K06Rik, anticorps AA420338, anticorps AI851081, anticorps Wdr40a, anticorps wdr40a, anticorps wu:fb93d04, anticorps zgc:154031, anticorps wdr40b, anticorps dcaf12, anticorps wdr40a-a, anticorps DDB1 and CUL4 associated factor 12, anticorps DDB1 and CUL4 associated factor 12 L homeolog, anticorps DCAF12, anticorps Dcaf12, anticorps dcaf12, anticorps dcaf12.L

Sujet:

Synonyms: cancer/testis antigen 102, Centrosome-related protein TCC52, CT102, DCA12_HUMAN, DCAF12, DDB1- and CUL4-associated factor 12, TCC52, Testis cancer centrosome-related protein, WD repeat domain 40A, WD repeat-containing protein 40A, WDR40A.

Background: WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WDR40A (WD-repeat-containing protein 40A), also known as DDB1- CUL4-associated factor 12, is a 453 amino acid cytoplasmic protein that contains four WD-repeats. WDR40A is highly expressed in some cancer cell lines, lung cancer tissues and normal testis. A probable substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex, WRD40A is suggested to interact with DDB1. WDR40A is encoded by a gene mapping to human chromosome 9p13.3. Human chromosome 9 houses over 900 genes and comprises nearly 4 % of the human genome.