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TMIGD1 anticorps (AA 160-200)

TMIGD1 Reactivité: Humain, Souris, Rat WB, IHC (p), IF (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1387070
  • Antigène Voir toutes TMIGD1 Anticorps
    TMIGD1 (Transmembrane and Immunoglobulin Domain Containing 1 (TMIGD1))
    Épitope
    • 1
    • 1
    AA 160-200
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 1
    • 1
    Lapin
    Clonalité
    • 1
    • 1
    Polyclonal
    Conjugué
    • 2
    Cet anticorp TMIGD1 est non-conjugé
    Application
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human TMIGD1
    Isotype
    IgG
    Top Product
    Discover our top product TMIGD1 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    TMIGD1 (Transmembrane and Immunoglobulin Domain Containing 1 (TMIGD1))
    Autre désignation
    TMIGD1 (TMIGD1 Produits)
    Synonymes
    anticorps RGD1307444, anticorps Tmigd, anticorps TMIGD, anticorps UNQ9372, anticorps 2010002A20Rik, anticorps transmembrane and immunoglobulin domain containing 1, anticorps Tmigd1, anticorps TMIGD1
    Sujet

    Synonyms: TMIGD, UNQ9372, Transmembrane and immunoglobulin domain-containing protein 1, TMIGD1, UNQ9372/PRO34164

    Background: Chromosome 17 makes up over 2.5 % of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dub? syndrome and Canavan disease are also associated with chromosome 17.

    ID gène
    388364
    UniProt
    Q6UXZ0
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