BMP10 anticorps (AA 350-400)

N° du produit ABIN1387078

Cet anticorps Lapin Polyclonal détecte spécifiquement BMP10 dans WB, IF (p) et IHC (p). Il présente une réactivité avec des échantillons de Humain.Il a été cité dans 1 publication.

Aperçu rapide pour BMP10 anticorps (AA 350-400) (ABIN1387078)

Antigène: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMP10 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-BMP10 anticorps

Épitope: AA 350-400

Fonction: BMP10 Polyclonal Antibody

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human BMP10

Isotype: IgG

Information d'application

Indications d'application: WB(1:100-500), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-BMP10 (ABIN1387078)

Wu, Chen, Mi, Chen, Wang, Gao: "Expression analysis of BMP2, BMP5, BMP10 in human colon tissues from Hirschsprung disease patients." dans: International journal of clinical and experimental pathology, Vol. 7, Issue 2, pp. 529-36, (2014) (PubMed).

Détails sur BMP10

Antigène: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Autre désignation: BMP10

Sujet:

Synonyms: Bone morphogenetic protein 1, BMP-1, BMP1

Background: Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.

ID gène: 27302

UniProt: O95393

Pathways: Hormone Activity, Regulation of Muscle Cell Differentiation