PROCR anticorps

N° du produit ABIN1387092

Cet anticorps anti-PROCR est un anticorps Lapin Polyclonal détectant PROCR dans WB, IHC (p) et IF (p). Adapté pour Humain, Souris et Rat. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour PROCR anticorps (ABIN1387092)

Antigène: PROCR (Protein C Receptor, Endothelial (PROCR))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PROCR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-PROCR anticorps

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human EPCR/CD201

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-PROCR (ABIN1387092)

Zhao, Ding, Liu, Yin, Zhang, Ma: "Unfractionated heparin protects the protein C system against lipopolysaccharide-induced damage in vivo and in vitro." dans: Experimental and therapeutic medicine, Vol. 14, Issue 6, pp. 5515-5522, (2017) (PubMed).

Détails sur PROCR

Antigène: PROCR (Protein C Receptor, Endothelial (PROCR))

Autre désignation: EPCR

Sujet:

Synonyms: Activated protein C receptor, APC receptor, APCR, CCCA, CCD41, CD201 antigen, centrocyclin, Endothelial cell protein C receptor, MGC23024, PROCR, EPCR_HUMAN, CD201.

Background: EPCR is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. It is an N glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. It is expressed strongly in the endothelial cells of arteries and veins in heart and lung. It is overexpressed in several human non-Pgp multidrug resistant (MDR) tumor cell lines. Whether and how anti-coagulant and anti-inflammatory functions of EPCR facilitate oncogenesis and/or drug resistance is unclear.

ID gène: 10544