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PDE4A anticorps

PDE4A Reactivité: Humain, Souris, Rat WB, IF (p), IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1387127
  • Antigène Voir toutes PDE4A Anticorps
    PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))
    Reactivité
    • 49
    • 35
    • 27
    • 8
    • 5
    • 5
    • 5
    • 3
    • 3
    Humain, Souris, Rat
    Hôte
    • 45
    • 4
    Lapin
    Clonalité
    • 47
    • 2
    Polyclonal
    Conjugué
    • 16
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PDE4A est non-conjugé
    Application
    • 46
    • 21
    • 12
    • 11
    • 10
    • 7
    • 7
    • 6
    • 3
    • 3
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human PDE4A8
    Isotype
    IgG
    Top Product
    Discover our top product PDE4A Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))
    Abstract
    PDE4A Produits
    Synonymes
    anticorps pde4, anticorps dpde2, anticorps pde46, anticorps PDE4A, anticorps Pde4a, anticorps D9Ertd60e, anticorps Dpde2, anticorps DPDE2, anticorps PDE4, anticorps PDE46, anticorps PHOSA, anticorps phosphodiesterase 4A S homeolog, anticorps phosphodiesterase 4A, cAMP-specific, anticorps phosphodiesterase 4A, anticorps phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila), anticorps cAMP-specific 3',5'-cyclic phosphodiesterase 4A, anticorps phosphodiesterase 4A, cAMP specific, anticorps phosphodiesterase 4C, anticorps pde4a.S, anticorps pde4a, anticorps PDE4A, anticorps LOC100009247, anticorps Pde4a, anticorps PDE4C
    Sujet

    Synonyms: 2EL, DPDE2, PDE4, PDE46, PDE4A, Phosphodiesterase 4A, Phosphodiesterse Type 4A8, PDE4A_HUMAN.

    Background: The PDE4A8 is a testis germ cell-specific PDE4A variant. There are two PDE4A variants identified in rat testis (PDE4A8 and an un-characterized 76 kDa PDE4A protein). Spermatogenesis is accompanied by expression of a varied repertoire of PDE4 enzymes at different stages of cell differentiation that presumably perform specialized functions. Confocal microscopic examination revealed the presence of PDE4A8 in primary and secondary spermatids but not in mature spermatozoa. PDE4A8 inhibition results in increased apoptosis of the germ cells accompanied with reduction in the number of mature spermatozoa.

    ID gène
    5141
    Pathways
    cAMP Metabolic Process
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