B4GALT7 anticorps

N° du produit ABIN1387134

Cet anticorps anti-B4GALT7 est un anticorps Lapin Polyclonal détectant B4GALT7 dans WB, IF (p) et IHC (p). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour B4GALT7 anticorps (ABIN1387134)

Antigène: B4GALT7 (Xylosylprotein beta 1,4-Galactosyltransferase, Polypeptide 7 (Galactosyltransferase I) (B4GALT7))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp B4GALT7 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-B4GALT7 anticorps

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human B4GALT7

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur B4GALT7

Antigène: B4GALT7 (Xylosylprotein beta 1,4-Galactosyltransferase, Polypeptide 7 (Galactosyltransferase I) (B4GALT7))

Autre désignation: B4GALT7

Sujet:

Synonyms: B4GAL T7, Beta 1,4 galactosyltransferase 7, Beta 1,4 GalTase 7, Beta4Gal T7, UDP Gal:beta GlcNAc beta 1,4 galactosyltransferase 7, XGALT 1, XGALT1, XGPT1, Xylosylprotein beta 1,4 galactosyltransferase, polypeptide 7, B4GT7_HUMAN.

Background: Beta-1,4-galactosyltransferases (beta-1,4-Gal-T) are type II membrane-bound glycoproteins that are substrate-specific and function to transfer galactose in a beta-1,4 linkage to an acceptor sugar. There are seven members of the beta-1,4-Gal-T family, all of which are directed to the golgi apparatus through a hydrophobic sequence at the N-terminus. Beta-1,4-Gal-T7, also known as B4GALT7 or XGALT1, is a 327 amino acid single-pass type II membrane protein that is expressed at high levels in heart, pancreas and liver. Beta-1,4-Gal-T7 uses manganese to catalyze the UDP-dependent biosynthesis of glycosphingolipids. The gene encoding beta-1,4-Gal-T7 is mutated in Ehlers-Danlos syndrome progeroid type (EDSP), a variant form of Ehlers-Danlos syndrome characterized by progeroid facies, mild mental retardation, short stature, skin hyperextensibility, moderate skin fragility, joint hypermobility principally in digits. Beta-1,4-galactosyltransferases (Beta-1,4-Gal-T) are type II membrane-bound glycoproteins that are substrate-specific and function to transfer galactose in a beta-1,4 linkage to an acceptor sugar.

ID gène: 11285

Pathways: Glycosaminoglycan Metabolic Process