BAALC anticorps

N° du produit ABIN1387199

Détail du produit anti-BAALC anticorps

Antigène: BAALC (Brain and Acute Leukemia, Cytoplasmic (BAALC))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAALC est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human BAALC

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur BAALC

Antigène: BAALC (Brain and Acute Leukemia, Cytoplasmic (BAALC))

Autre désignation: BAALC (BAALC Produits)

Synonymes: anticorps si:zc215i13.3, anticorps si:ch211-215i13.3, anticorps BAALC, anticorps 2810457D07Rik, anticorps BAALC, MAP3K1 and KLF4 binding, anticorps brain and acute leukemia, cytoplasmic, anticorps BAALC, anticorps baalc, anticorps Baalc

Sujet:

Synonyms: BAALC, BAALC_HUMAN, Brain and acute leukemia cytoplasmic, Brain and acute leukemia cytoplasmic protein, brain and acute leukemia, cytoplasmic, FLJ12015.

Background: BAALC is a 180 amino acid protein that localizes to both the membrane and the cytoplasm and exists as multiple alternatively spliced isoforms. Expressed by hematopoetic and neural cells, BAALC interacts with CaMKII and is thought to play a role in synaptic function at postsynaptic lipid rafts. BAALC may be overexpressed in acute myeloid leukemia (AML), suggesting a role in tumorigenesis. The gene encoding BAALC maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that maps to chromosome 8.

ID gène: 79870