TNNC1 anticorps (pThr143)

N° du produit ABIN1387204

Cet anticorps Lapin Polyclonal détecte spécifiquement TNNC1 dans IF (p) et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour TNNC1 anticorps (pThr143) (ABIN1387204)

Antigène: TNNC1 (Cardiac Troponin C (TNNC1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNNC1 est non-conjugé

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-TNNC1 anticorps

Épitope: pThr143

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human cardiac around the phosphorylation site of Troponin I Thr143

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur TNNC1

Antigène: TNNC1 (Cardiac Troponin C (TNNC1))

Autre désignation: cardiac Troponin I

Sujet:

Synonyms: cardiac Troponin I phospho Thr143, p-cardiac Troponin I Thr143, cardiac Troponin I phospho T143, p-cardiac Troponin I T143, Cardiac troponin I, Cardiomyopathy, familial hypertrophic, 7, included, CMD1FF, CMD2A, CMH7, cTnI, Familial hypertrophic cardiomyopathy 7, MGC116817, RCM1, p-Tn1, p-Tni, TNN I3, p-TNNC 1, p-TNNC1, p-TNNI3, p-Troponin I cardiac, Troponin I cardiac muscle, Troponin I cardiac muscle isoform, Troponin I type 3 cardiac, troponin I, cardiac 3, TroponinI, TNNI3_HUMAN.

Background: Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq].

ID gène: 7137