FKBP4 anticorps (AA 1-100)

N° du produit ABIN1387268

L’anticorps Lapin Polyclonal anti-FKBP4 a été validé pour WB, ELISA, ICC, IHC (p), IF (p), IF (cc) et IHC (fro). Il convient pour détecter FKBP4 dans des échantillons de Humain.

Aperçu rapide pour FKBP4 anticorps (AA 1-100) (ABIN1387268)

Antigène: FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FKBP4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-FKBP4 anticorps

Épitope: AA 1-100

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HSP56

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur FKBP4

Antigène: FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))

Autre désignation: HSP56/FKBP52

Sujet:

Synonyms: Hsp 56, HSP binding immunophilin, HSP-binding immunophilin, Hsp56, N-terminally processed, 51 kDa FK506-binding protein, 52 kDa FK506 binding protein, 52 kDa FK506-binding protein, 52 kDa FKBP, 59 kDa immunophilin, FK506 binding protein 4, FK506-binding protein 4, FKBP 4, FKBP 52, FKBP 59, FKBP-4, FKBP-52, FKBP4, FKBP4_HUMAN, FKBP51, FKBP52 protein, FKBP59, HBI, Immunophilin FKBP52, p52 antibody p59 antibody p59 protein, Peptidyl prolyl cis trans isomerase, Peptidyl-prolyl cis-trans isomerase FKBP4, Peptidylprolyl cis trans isomerase, PPIase, PPIase FKBP4, Rotamase, T cell FK506 binding protein 59kD.

Background: HSP56 is a cis-trans prolyl isomerase belonging to the immunophilin protein family. The human HSP 56 gene (FKBP4) has multiple polyadenylation sites and the HSP 56 protein can undergo phosphorylation. HSP 56 influences immunoregulatory gene expression in lymphocytes, protein folding and trafficking. It can serve as a co-chaperone for steroid hormone nuclear receptors to govern appropriate hormone action in target tissues. The protein can associate with phytanoyl-CoA alpha-hydroxylase (PHYH) and with HSP90 through a series of tetratricopeptide repeat (TPR) domains. HSP 56 is a TRPC ion channel accessory protein that modulates channel activation following receptor stimulation.

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway