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OSTM1 anticorps (AA 21-120)

OSTM1 Reactivité: Humain, Rat, Souris WB, ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1387308
  • Antigène Voir toutes OSTM1 Anticorps
    OSTM1 (Osteopetrosis Associated Transmembrane Protein 1 (OSTM1))
    Épitope
    • 15
    • 8
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    Reactivité
    • 37
    • 19
    • 19
    • 3
    Humain, Rat, Souris
    Hôte
    • 37
    • 1
    Lapin
    Clonalité
    • 37
    • 1
    Polyclonal
    Conjugué
    • 10
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp OSTM1 est non-conjugé
    Application
    • 38
    • 16
    • 16
    • 12
    • 12
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human OSTM1
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    OSTM1 (Osteopetrosis Associated Transmembrane Protein 1 (OSTM1))
    Autre désignation
    OSTM1 (OSTM1 Produits)
    Synonymes
    anticorps MGC145644, anticorps si:ch73-257c13.3, anticorps GIPN, anticorps GL, anticorps OPTB5, anticorps 1200002H13Rik, anticorps HSPC019, anticorps gl, anticorps Gipn, anticorps OSTM1, anticorps osteopetrosis associated transmembrane protein 1, anticorps OSTM1, anticorps ostm1, anticorps Ostm1
    Sujet

    Synonyms: GL, GIPN, OPTB5, HSPC019, Osteopetrosis-associated transmembrane protein 1, Chloride channel 7 beta subunit, OSTM1, UNQ6098/PRO21201

    Background: OSTM1 (osteopetrosis associated transmembrane protein 1), also known as gl (gray-lethal) or HSPC019, is a 338 amino acid single-pass type I membrane protein that is expressed primarily in osteoclasts and melanocytes as well as brain, kidney and spleen. Bone autosomal recessive osteopetrosis (ARO) is the most severe form of hereditary bone disease whose cellular basis is in the osteoclast and is characterized by abnormally dense bone, due to defective resorption of immature bone. ARO is suggested to be caused by mutations in the OSTM1 gene. The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or adulthood. Defects in the OSTM1 gene are also the cause of the spontaneous gl mutant, which is responsible for a coat color defect in mice.

    ID gène
    28962
    UniProt
    Q86WC4
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