Mycobacterium Tuberculosis Ag85 anticorps
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- Antigène
- Mycobacterium Tuberculosis Ag85
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Reactivité
- Mycobacterium tuberculosis
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Inconjugué
- Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- This antibody will recognize Mycobacterium tuberculosis Ag85A and Ag85B
- Réactivité croisée
- Bactéries
- Réactivité croisée (Details)
- Mycobacteriumtuberculosis
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from Mycobacterium tuberculosis Ag85B
- Isotype
- IgG
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- Indications d'application
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WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- Mycobacterium Tuberculosis Ag85
- Autre désignation
- Mycobacterium Tuberculosis Ag85B
- Sujet
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Synonyms: Antigen 85 complex B, 30 kDa extracellular protein, Mycobacterium, Mycolyl transferase 85B, fbpB, Antigen 85-B, 85B, Ag85B, Extracellular alpha-antigen, Fibronectin-binding protein B, DGAT, Acyl-CoA:diacylglycerol acyltransferase, Ag85A, fbpA, 85A
Background: The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM.
- ID gène
- 885785, 886132
- UniProt
- P9WQP1, P9WQP3
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