LRRTM3 anticorps (AA 31-120)

N° du produit ABIN1387364

L’anticorps anti-LRRTM3 Polyclonal Lapin est utilisé pour la détection de LRRTM3 dans des échantillons de Souris. Il a été validé pour WB, FACS et ELISA.

Aperçu rapide pour LRRTM3 anticorps (AA 31-120) (ABIN1387364)

Antigène: LRRTM3 (Leucine Rich Repeat Transmembrane Neuronal 3 (LRRTM3))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRRTM3 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Détail du produit anti-LRRTM3 anticorps

Épitope: AA 31-120

Réactivité croisée: Souris

Homologie: Human,Rat,Cow,Sheep,Pig,Chicken,Rabbit,Monkey

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human LRRTM3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur LRRTM3

Antigène: LRRTM3 (Leucine Rich Repeat Transmembrane Neuronal 3 (LRRTM3))

Autre désignation: LRRTM3

Sujet:

Synonyms: Leucine rich repeat transmembrane neuronal protein 3, Leucine-rich repeat transmembrane neuronal protein 3, LRRT3_HUMAN, Lrrtm3, MGC131810, PRO1693, UNQ803.

Background: The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic Alpha/Beta horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The LRRTM protein family plays a role in the regulation of various cellular events during nervous system development. Localizing predominantly to the nervous system, LRRTM family members are known to exhibit synaptogenic activity. LRRTM3 (leucine rich repeat transmembrane neuronal 3) is a 581 amino acid single-pass type I membrane protein belonging to the LRRTM family. LRRTM3 is involved in the development and maintenance of the vertebrate nervous system, and contains ten LRR repeats. Expressed in neuronal tissues, LRRTM3 is encoded by a gene that maps to a region of chromosome 10 that has been linked to late-onset Alzheimer disease and elevated plasma Beta-Amyloid. As a result of alternative splicing events, two LRRTM3 isoforms exist.

Pathways: Synaptic Membrane