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CBLN2 anticorps (AA 151-224)

L’anticorps Lapin Polyclonal anti-CBLN2 a été validé pour WB, ELISA, IF (cc), IF (p), IHC (p), ICC et IHC (fro). Il convient pour détecter CBLN2 dans des échantillons de Rat.
N° du produit ABIN1387526

Aperçu rapide pour CBLN2 anticorps (AA 151-224) (ABIN1387526)

Antigène

CBLN2 (Cerebellin 2 Precursor (CBLN2))

Reactivité

  • 25
  • 23
  • 20
  • 2
  • 1
  • 1
Rat

Hôte

  • 37
Lapin

Clonalité

  • 37
Polyclonal

Conjugué

  • 11
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp CBLN2 est non-conjugé

Application

  • 30
  • 14
  • 12
  • 12
  • 8
  • 5
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Épitope

    • 14
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    AA 151-224

     Réactivité croisée

    Rat

    Homologie

    Human,Mouse,Dog,Cow,Pig,Horse,Rabbit

    Purification

    Purified by Protein A.

    Immunogène

    KLH conjugated synthetic peptide derived from human CBLN2

    Isotype

    IgG
  • Indications d'application

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Date de péremption

    12 months
  • Antigène

    CBLN2 (Cerebellin 2 Precursor (CBLN2))

    Autre désignation

    CBLN2

    Sujet

    Synonyms: A730004O05, Cbln2, CBLN2_HUMAN, Cerebellin 2, Cerebellin 2 precursor, Cerebellin-2, OTTHUMP00000163726.

    Background: Cerebellin (CER), which was originally isolated from rat cerebellum, is a hexadecapeptide derived from a larger precursor Cerebellin 1, also designated precerebellin 1 or Cbln1. Four propeptides, Cerebellin 1, Cerebellin 2 (Cbln2), Cerebellin 3 (Cbln3), and Cerebellin 4 (Cbln4), comprise the precerebellin subfamily within the C1q protein family. Cerebellin family members act as transneuronal regulators of synapse development and synaptic plasticity in various brain regions. CER and it metabolite des-Ser1-cerebellin are also expressed in several extra-cerebellar tissues, including adrenal gland. Cerebellin 1, 2 and 3 assemble into homomeric and heteromeric complexes, thereby influencing each other?s degradation and secretion. Cerebellin 3 is not able to form homomeric complexes, and can only be secreted upon forming a heteromeric complex with Cerebellin 1. Decreased concentrations of CER has been found in the brain of patients with olivopontocerebellar atrophy (OPCA) and Shy-Drager syndrome, suggesting a role for CER in the pathology of these diseases.

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