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TNIP1 anticorps

TNIP1 Reactivité: Humain, Souris, Rat WB, IHC (p), IF (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1387564
  • Antigène Voir toutes TNIP1 Anticorps
    TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))
    Reactivité
    • 47
    • 5
    • 4
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 44
    • 3
    Lapin
    Clonalité
    • 46
    • 1
    Polyclonal
    Conjugué
    • 20
    • 5
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TNIP1 est non-conjugé
    Application
    • 37
    • 29
    • 18
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human TNIP1
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Zhou, Lu, Wang, Li, Luo: "A20-Binding Inhibitor of NF-κB 1 Ameliorates Neuroinflammation and Mediates Antineuroinflammatory Effect of Electroacupuncture in Cerebral Ischemia/Reperfusion Rats." dans: Evidence-based complementary and alternative medicine : eCAM, Vol. 2020, pp. 6980398, (2020) (PubMed).

  • Antigène
    TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))
    Autre désignation
    TNIP1 (TNIP1 Produits)
    Synonymes
    anticorps ABIN-1, anticorps NAF1, anticorps VAN, anticorps nip40-1, anticorps ABIN, anticorps ABIN1, anticorps AU018810, anticorps Naf1, anticorps Nef, anticorps im:7141452, anticorps naf1, anticorps zgc:158159, anticorps tnip1, anticorps MGC147597, anticorps TNFAIP3 interacting protein 1, anticorps TNFAIP3 interacting protein 1 S homeolog, anticorps TNFAIP3-interacting protein 1, anticorps TNIP1, anticorps Tnip1, anticorps tnip1, anticorps tnip1.S, anticorps LOC100078195
    Sujet

    Synonyms: ABIN 1, ABIN-1, abin1, HIV-1 Nef interacting protein Nip40-1, TNFAIP3 interacting protein 1, HIV-1 Nef interacting protein, HIV-1 Nef-interacting protein, hVAN, KIAA0113, NAF 1, NAF-1, NAF1, Nef-associated factor 1, Nef-associated factor 1 SNP, Nip 40-1, Nip40-1, TNFAIP3 interacting protein 1, TNFAIP3-interacting protein 1, TNIP 1, TNIP-1, Tnip1, TNIP1_HUMAN, VAN, Virion associated nuclear shuttling protein, Virion-associated nuclear shuttling protein.

    Background: Abin-1 is a 636 amino acid protein that localizes to both the nucleus and the cytoplasm and is shuttled between the two intercellular regions in a CRM1-dependent manner. Expressed ubiquitously with highest expression in spleen and skeletal muscle, Abin-1 interacts with A20 and, via this interaction, interferes with TRAF2-mediated transactivation signals and effectively inhibits TNF-induced NF_B expression. Additionally, Abin-1 can be incorporated into HIV-1 virions and, if overexpressed, can inhibit viral replication. Abin-1 may also play an important role in the regulation of nuclear import and export activities. Multiple isoforms of Abin-1 exist due to alternative splicing events.

    Pathways
    Activation of Innate immune Response
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