Sulfiredoxin 1 anticorps (AA 45-137)
Aperçu rapide pour Sulfiredoxin 1 anticorps (AA 45-137) (ABIN1387599)
Antigène
Voir toutes Sulfiredoxin 1 (SRX1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 45-137
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Réactivité croisée
- Humain, Souris, Rat
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Homologie
- Dog,Cow,Pig,Horse,Chicken,Rabbit
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human SRXN1
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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: "Sulfiredoxin-1 protects against simulated ischaemia/reperfusion injury in cardiomyocyte by inhibiting PI3K/AKT-regulated mitochondrial apoptotic pathways." dans: Bioscience reports, Vol. 36, Issue 2, (2016) (PubMed).
: "Sulfiredoxin-1 exerts anti-apoptotic and neuroprotective effects against oxidative stress-induced injury in rat cortical astrocytes following exposure to oxygen-glucose deprivation and hydrogen ..." dans: International journal of molecular medicine, Vol. 36, Issue 1, pp. 43-52, (2015) (PubMed).
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: "Sulfiredoxin-1 protects against simulated ischaemia/reperfusion injury in cardiomyocyte by inhibiting PI3K/AKT-regulated mitochondrial apoptotic pathways." dans: Bioscience reports, Vol. 36, Issue 2, (2016) (PubMed).
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- Sulfiredoxin 1 (SRX1)
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Autre désignation
- SRXN1
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Sujet
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Synonyms: SRX, Npn3, SRX1, C20orf139, Sulfiredoxin-1, SRXN1
Background: Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase.
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ID gène
- 140809
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UniProt
- Q9BYN0
Antigène
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