DOK5 anticorps (AA 21-120)
Aperçu rapide pour DOK5 anticorps (AA 21-120) (ABIN1387610)
Antigène
Voir toutes DOK5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 21-120
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Réactivité croisée
- Humain
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Homologie
- Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human DOK5/IRS6
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Isotype
- IgG
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Indications d'application
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ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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: "Dok5 is involved in the signaling pathway of neurotrophin-3 against TrkC-induced apoptosis." dans: Neuroscience letters, Vol. 553, pp. 46-51, (2013) (PubMed).
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: "Dok5 is involved in the signaling pathway of neurotrophin-3 against TrkC-induced apoptosis." dans: Neuroscience letters, Vol. 553, pp. 46-51, (2013) (PubMed).
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- DOK5 (Docking Protein 5 (DOK5))
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Autre désignation
- DOK5
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Sujet
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Synonyms: IRS6, IRS-6, C2orf18, Docking protein 5, Downstream of tyrosine kinase 5, Insulin receptor substrate 6, DOK5
Background: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.
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ID gène
- 55816
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UniProt
- Q9P104
Antigène
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