NCAM2 anticorps (AA 51-150)

N° du produit ABIN1387627

Cet anticorps Lapin Polyclonal détecte spécifiquement NCAM2 dans ELISA et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour NCAM2 anticorps (AA 51-150) (ABIN1387627)

Antigène: NCAM2 (Neural Cell Adhesion Molecule 2 (NCAM2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCAM2 est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Détail du produit anti-NCAM2 anticorps

Épitope: AA 51-150

Réactivité croisée: Humain

Homologie: Mouse,Rat,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human NCAM2

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
FCM 1:20-100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur NCAM2

Antigène: NCAM2 (Neural Cell Adhesion Molecule 2 (NCAM2))

Autre désignation: NCAM2

Sujet:

Synonyms: N CAM 2, N CAM 21, N CAM2, N CAM21, N-CAM-2, NCAM 2, NCAM 21, NCAM-2, Ncam2, NCAM2_HUMAN, NCAM21, Neural cell adhesion molecule 2, OCAM GPI, R4B12, RB 8 neural cell adhesion molecule, RB8 neural cell adhesion molecule, RNCAM.

Background: NCAM2 is an 837 amino acid protein encoded by the human gene NCAM2. NCAM2 contains five immunoglobulin-like domains, two Fibronectin type III domains, a transmembrane domain and a cytoplasmic domain. The gene is expressed most strongly in human adult and fetal brain. NCAM2 is a member of the neural cell adhesion molecule (NCAM) family. NCAMs are closely related cell surface glycoproteins involved in cell to cell interactions during growth and are thought to play an important role in embryogenesis and development. NCAM2 is a considered a good candidate for involvement in certain Down syndrome phenotypes because a slight overexpression of NCAMs increases many-fold the homotypic adhesion properties of cells. Stat5 regulates NCAM2 in vivo by binding to the NCAM2 intron in the NKL natural killer cell line, this binding is induced by cytokines that activate Stat5. Neither Stat1 nor Stat3 bind to this region, despite sharing a consensus binding sequence with Stat5.