SYT11 anticorps (AA 51-100)

N° du produit ABIN1387635

Détail du produit anti-SYT11 anticorps

Antigène: SYT11 (Synaptotagmin XI (SYT11))

Épitope: AA 51-100

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SYT11 est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Synaptotagmin XI

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur SYT11

Antigène: SYT11 (Synaptotagmin XI (SYT11))

Autre désignation: Synaptotagmin 11 (SYT11 Produits)

Synonymes: anticorps SYT12, anticorps sytXI, anticorps 1500004A13Rik, anticorps 3632445O20Rik, anticorps 5430404N14Rik, anticorps 6530420C11Rik, anticorps AI851970, anticorps syt11, anticorps fc52d10, anticorps fi68d01, anticorps zgc:55556, anticorps wu:fc52d10, anticorps wu:fi68d01, anticorps SYT11, anticorps DKFZp459M023, anticorps synaptotagmin 11, anticorps synaptotagmin XI, anticorps synaptotagmin XIa, anticorps synaptotagmin XIb, anticorps SYT11, anticorps Syt11, anticorps syt11a, anticorps syt11, anticorps syt11b

Sujet:

Synonyms: Synaptotagmin 11, Synaptotagmin 12, Synaptotagmin XI, Synaptotagmin-11, synaptotagmin XII, synaptotagmin-XII, Synaptotagmin11, Synaptotagmin12, Synaptotagmin-11, Synaptotagmin-12, SynaptotagminXI, SYT 11, SYT 12, SYT-11, SYT-12, Syt XI, Syt11, SYT11_HUMAN, SYT12, SytXI, DKFZp781D015, KIAA0080, MGC10881, MGC17226.

Background: Synaptotagmins are a large family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. Synaptotagmin XI, also known as SYT11 (Synaptotagmin-11), is a 431 amino acid protein that localizes to the membrane and is expressed ubiquitously with highest expression in brain and lung. Like other Synaptotagmin proteins, Synaptotagmin XI is involved in the calcium-dependent exocytosis of secretory vesicles and is thought to act as a calcium sensor during vesicular trafficking. Synaptotagmin XI contains two C2 domains through which it can bind either three calcium ions or the zinc-finger protein Parkin (a juvenile Parkinson?s disease gene product), the latter of which causes the polyubiquitination and subsequent degradation of Synaptotagmin XI by the proteasome complex. Defects in the gene encoding Synaptotagmin XI are implicated in a number of neurological disorders, including schizophrenia and Parkinson?s disease.

ID gène: 23208