PHF21A anticorps (AA 351-450)
Aperçu rapide pour PHF21A anticorps (AA 351-450) (ABIN1387678)
Antigène
Voir toutes PHF21A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 351-450
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Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human PHF21A
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Isotype
- IgG
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Indications d'application
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- PHF21A (PHD Finger Protein 21A (PHF21A))
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Autre désignation
- BHC80/PHF21A
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Sujet
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Synonyms: BHC80a, BM-006, BRAF35-HDAC complex protein BHC80, BRAF35-HDAC complex protein BHC80, BRAF35-HDAC complex protein BHC80, BRAF35/HDAC2 complex 80 kDa, KIAA1696, PF21A_HUMAN, PHD finger protein 21A, PHF21A.
Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. PHF21A is a 680 amino acid nuclear protein that contains one PHD-type zinc finger and one A.T hook DNA-binding domain, suggesting involvement in transcriptional regulation events. PHF21A is a component of the BHC complex, which is responsible for repressing transcription of neuron-specific genes in non-neuronal cells. The BHC complex acts as a chromatin modifier that deacetylates and demethylates specific sites on histones. PHF21A may act as a scaffold within the BHC complex. Predominantly expressed in brain, three isoforms of PHF21A exist as a result of alternative splicing events.
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ID gène
- 51317
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Pathways
- Feeding Behaviour
Antigène
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