RCAN3 anticorps (AA 151-241)

N° du produit ABIN1387777

Cet anticorps Lapin Polyclonal détecte spécifiquement RCAN3 dans WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) et ICC. Il présente une réactivité avec des échantillons de Souris et Rat.

Aperçu rapide pour RCAN3 anticorps (AA 151-241) (ABIN1387777)

Antigène: RCAN3 (RCAN Family Member 3 (RCAN3))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RCAN3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Détail du produit anti-RCAN3 anticorps

Épitope: AA 151-241

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Sheep,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Calcipressin 3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur RCAN3

Antigène: RCAN3 (RCAN Family Member 3 (RCAN3))

Autre désignation: Calcipressin 3

Sujet:

Synonyms: Calcipressin-3, Down syndrome candidate region 1 like 2, regulator of calcineurin 3, Down syndrome candidate region 1 like protein 2, Down syndrome candidate region 1-like protein 2, Down syndrome critical region gene 1 like 2, DSCR1L2, hRCN3, MCIP3, Myocyte enriched calcineurin interacting protein 3, Myocyte-enriched calcineurin-interacting protein 3, RCAN family member 3, RCAN3, RCAN3_HUMAN, RCN3, Regulator of calcineurin 3.

Background: Calcineurin is a Ca(2+) dependent protein phosphatase that is involed in several neuornal functions. Proteins belonging to the RCAN (Regulator of calcineurin) family modulate the activity of Calcineurin through a valine-rich region within their carboxyl tail. RCANs compete with NFATs (Nuclear factor of activated T-cells) for binding to the same docking site in calcineurin, which results in either inhibition or activation of calcineurin activity. Calcipressin-2, also known as RCAN2 and DSCR1L1 (Down syndrome candidate region 1-like 1), is a 197 amino acid protein that is highly expressed in both the cytoplasm and nucleus of neurons and is the only RCAN family member that is found in glial cells. Calcipressin-3, also known as RCAN3 and DSCR1L2 (Down syndrome candidate region 1-like protein 2), is a 241 amino acid protein that potentially is involved in central nervous system development. Calcipressin-3 interacts with cardiac troponin I, suggesting that it may play a role in cardiac contraction events.