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CHRND anticorps (AA 145-190)

Cet anticorps anti-CHRND est un anticorps Lapin Polyclonal détectant CHRND dans ELISA, ICC, IHC (p), IF (cc), IF (p) et IHC (fro). Adapté pour Humain.
N° du produit ABIN1387797

Aperçu rapide pour CHRND anticorps (AA 145-190) (ABIN1387797)

Antigène

Voir toutes CHRND Anticorps
CHRND (Cholinergic Receptor, Nicotinic, delta (Muscle) (CHRND))

Reactivité

  • 29
  • 7
  • 7
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
Humain

Hôte

  • 27
  • 2
Lapin

Clonalité

  • 27
  • 2
Polyclonal

Conjugué

  • 21
  • 2
  • 2
  • 2
  • 1
  • 1
Cet anticorp CHRND est non-conjugé

Application

  • 24
  • 15
  • 10
  • 3
  • 3
  • 1
  • 1
ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Épitope

    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 145-190

    Homologie

    Human,Mouse,Rat,Dog,Pig,Horse,Rabbit

    Purification

    Purified by Protein A.

    Immunogène

    KLH conjugated synthetic peptide derived from human CHRND

    Isotype

    IgG
  • Indications d'application

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Date de péremption

    12 months
  • Antigène

    CHRND (Cholinergic Receptor, Nicotinic, delta (Muscle) (CHRND))

    Autre désignation

    CHRND

    Sujet

    Synonyms: Acetylcholine receptor delta subunit, Acetylcholine receptor subunit delta, ACHD_HUMAN, ACHRD, Cholinergic receptor, nicotinic, delta polypeptide, CHRND, CMS2A, FCCMS, Nicotinic acetylcholine receptor delta polypeptide precursor, SCCMS.

    Background: Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters. Two important members of this family are the nicotinic acetylcholine and glutamate receptors, both of which are composed of five homologous subunits forming a transmembrane aqueous pore. These transmembrane receptors change conformation in response to their cognate neurotransmitter. Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, allowing ions to move through the pore. Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system. The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, an enzyme that rapidly hydrolyzes acetylcholine. AChR delta, also known as CMS2A, FCCMS, SCCMS or CHRND, is a 517 amino acid multi-pass membrane protein that is associated with lethal type multiple pterygium syndrome, congenital myasthenic syndrome slow-channel type (SCCMS) and congenital myasthenic syndrome fast-channel type (FCCMS).

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