RCAN1 anticorps (AA 101-200)

N° du produit ABIN1387813

Cet anticorps Lapin Polyclonal détecte spécifiquement RCAN1 dans WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) et ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour RCAN1 anticorps (AA 101-200) (ABIN1387813)

Antigène: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RCAN1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Détail du produit anti-RCAN1 anticorps

Épitope: AA 101-200

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Calcipressin 1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur RCAN1

Antigène: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Autre désignation: Calcipressin 1/DSCR 1

Sujet:

Synonyms: Adapt 78, Adapt78, Calcipressin 1, Calcipressin-1, Calcium and oxidant inducible mRNA, CSP 1, CSP1, Down syndrome candidate region 1, Down syndrome critical region gene 1, Down syndrome critical region protein 1, DSC 1, DSC1, DSCR 1, DSCR1, DSCR-1, MCIP 1, MCIP1, Modulatory calcineurin interacting protein 1, Myocyte enriched calcineurin interacting protein 1, Myocyte-enriched calcineurin-interacting protein 1, Near DSCR proline rich protein, RCAN1, RCAN1_HUMAN, RCN 1, RCN1, Regulator of calcineurin 1.

Background: DSCR1 protein influences cardiac and nervous system development (1). DSCR1 is abundant in the brain, heart, and skeletal muscle. Overexpression of DSCR1 may play a role in the pathogenesis of Down syndrome, in particular mental retardation and/or cardiac defects. DSCR1 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Human DSCR1 maps to gene locus 21q22.1-q22.2.

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development