HSP70 1A/ 1B (AA 500-600) anticorps

N° du produit ABIN1387822

Cet anticorps Lapin Polyclonal détecte spécifiquement HSP70 1A/ 1B dans WB, FACS, IHC (p) et ELISA. Il présente une réactivité avec des échantillons de Humain, Poulet, Souris, Porc et Rat. Il a été cité dans 2+ publications.

Aperçu rapide pour HSP70 1A/ 1B (AA 500-600) anticorps (ABIN1387822)

Antigène: HSP70 1A/ 1B

Reactivité: Humain, Poulet, Souris, Porc, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA

Détail du produit

Épitope: AA 500-600

Réactivité croisée: Poulet, Humain, Souris, Porc, Rat

Homologie: Cow,Sheep,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HSP70 1A/1B

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Référence

Oyagbemi, Omobowale, Ola-Davies, Asenuga, Ajibade, Adejumobi, Arojojoye, Afolabi, Ogunpolu, Falayi, Hassan, Ochigbo, Saba, Adedapo, Yakubu: "Quercetin attenuates hypertension induced by sodium fluoride via reduction in oxidative stress and modulation of HSP 70/ERK/PPARγ signaling pathways." dans: BioFactors (Oxford, England), Vol. 44, Issue 5, pp. 465-479, (2019) (PubMed).

Zheng, Liu, Li, Tang, Zhang, Tang: "Lithium posttreatment confers neuroprotection through glycogen synthase kinase-3β inhibition in intracerebral hemorrhage rats." dans: Journal of neurosurgery, pp. 1-9, (2016) (PubMed).

Détail du antigène

Antigène: HSP70 1A/ 1B

Autre désignation: HSP70 1A/1B

Sujet:

Synonyms: HSP72, HSPA1, HSP70I, HSP70-1, HSP70-1A, HEL-S-103, Heat shock 70 kDa protein 1A/1B, Heat shock 70 kDa protein 1/2, HSP70-1/HSP70-2, HSP70.1/HSP70.2, HSPA1A, HSX70

Background: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.

ID gène: 3303

UniProt: P08107