ESR2 anticorps (pSer87)

N° du produit ABIN1387942

Cet anticorps Lapin Polyclonal détecte spécifiquement ESR2 dans WB et ELISA. Il présente une réactivité envers Souris.

Aperçu rapide pour ESR2 anticorps (pSer87) (ABIN1387942)

Antigène: ESR2 (Estrogen Receptor 2 (ESR2))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ESR2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ESR2 anticorps

Épitope: pSer87

Réactivité croisée: Souris

Homologie: Human,Rat,Sheep,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human Estrogen Receptor beta around the phosphorylation site of Ser87 [HL(p-S)PL]

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur ESR2

Antigène: ESR2 (Estrogen Receptor 2 (ESR2))

Autre désignation: Estrogen Receptor beta

Sujet:

Synonyms: Estrogen Receptor beta phospho S87, Estrogen Receptor beta phospho Ser87, p-ER betaS87, p-ER betaSer87, ER-betaSer87, ER-betaS87, Estrogen receptor-beta, ER BETA, ER-BETA, ER-beta, Erb, ESR 2, ESR 2, ESR B, ESR-B, ESR BETA, ESR-BETA, ESR2, ESR2, ESR2_HUMAN, ESRB, ESTRB, estrogen nuclear receptor beta variant a, estrogen nuclear receptor beta variant b, estrogen receptor 2 ER beta, Estrogen Receptor 2, Estrogen Receptor-2, estrogen receptor beta 4, Estrogen receptor beta, NR3A2, Nuclear receptor subfamily 3 group A member 2.

Background: Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ER alpha and ER beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. ER alpha and ER beta A have been shown to be differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ER alpha and ER beta may be regulated by distinct mechanisms even though they share many functional characteristics.

ID gène: 2100

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling